| Thursday, November 8, 2007: 8:30 AM-11:00 AM | |||
| M - Salon E (Marriott Salt Lake City-Downtown) | |||
Topical I: Pharmaceutical Engineering for the 21^st Century (TI) | |||
| #551 - Particle Engineering in the Active Pharmaceutical Ingredient and Drug Product Manufacturing (TI014) | |||
| Physical properties of pharmaceutical particles are greatly affected by particle size distribution and morphology. In many occasions the particles need to be engineered to meet certain formulation and process requirements. This session highlights advances in particle engineering to address process and formulation issues in the pharmaceutical industry. Particle engineering techniques in both API synthesis and drug product formulation are welcome. Sample cases include production of small crystals to improve bioavailability or compactability, particle size enlargement or morphology modification to improve powder flowability and bulk density, and granulation to improve drug product formulation processes, etc. | |||
| Chair: | Bing-Shiou Yang | ||
| CoChair: | Praveen K. Sharma | ||
| CoSponsor(s): | Pharmaceuticals (15b) | ||
| 8:30 AM | 551a | Seeding--Friend or Foe? San Kiang, Chiajen Lai, Thomas LaPorte, Fernando Quiroz, Lori Spangler, Jean Tom, Zhongmin Xu | |
| 8:50 AM | 551b | A High Intensity Emulsification Method For The Production Of Nanoparticles Eric Jayjock, M. Silvina Tomasone, Fernando J. Muzzio | |
| 9:10 AM | 551c | Precipitation of Micro/nanoparticles by Enhanced Energy Dissipating Impinging Jets in Stirred-Tank Reactors Giuseppe Di Benedetto, Ewa Sukcik, Piero M. Armenante, Somenath Mitra | |
| 9:30 AM | 551d | Development of a Particle Size Analysis Method for Dry and Wet Granulation Jennifer Wang, Niranjan Kottala, Robert Jerzewski, Emil Friedman | |
| 9:50 AM | Break | ||
| 10:00 AM | 551e | Computational Modelling Of The Anderson Cascade Impactor Eric Jayjock, Justin P. Lacombe, Fernando J. Muzzio | |
| 10:20 AM | 551f | Controlled Nanoparticle Agglomeration As A Low-Density Dry Powder Aerosol Formulation Strategy Lianjun Shi, Laura J. Peek, Carl Plumley, Mark Bailey, Cory Berkland | |
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