Thursday, November 8, 2007: 12:30 PM-3:00 PM
M - Salon E (Marriott Salt Lake City-Downtown)

Topical I: Pharmaceutical Engineering for the 21^st Century (TI)

#565 - Absorption of Oral Dosage Forms (TI000)
Papers are invited from industry and academia on cutting edge studies focusing on the absorption and bioavailability of oral dosage forms. Subjects include and are not limited to: formulation design and bioavailability enhancing platforms, modeling of the pharmacokinetic, absorption, and hydrodynamic profiles of dosage forms within the GI tract, in-vitro-in-vivo correlations for dissolution of oral dosage forms, innovative processing techniques in controlled release and immediate release oral delivery, and studies relating GI physiology to absorption profiles.
Chair:Padma J. Narayan
CoChair:Monica Adams
CoSponsor(s):Pharmaceuticals (15b)
12:30 PMOral Absorption of Weakly Acidic Compounds
Monica L. Adams, Venkatramana Rao, James Ormes, Ajit Thakur
12:55 PMOral Delivery of Insulin-Transferrin Bioconjugates Using Intelligent Complexation Hydrogels
Justin P. Shofner, Nicholas A. Peppas
1:20 PMDevelopment of A Computer Program Predicting the Influence of Cyclodextrins on Oral Bioavailability of Insoluble Drugs: From Modeling to in Vivo Comparison
Ece D. Gamsiz, Lee A. Miller, Avinash G. Thombre, Rebecca L. Carrier
1:45 PMUsing Physically-Based Dissolution Simulations to Develop Ideal Particle Distributions in Tablets
Dan Braido, Alberto Cuitino
2:10 PMA New Hypromellose Excipient for Direct Compression Controlled Release
Karl Jacob, Kacee Ender, Tim Cabelka, Dan Denomme, Dave Wallick
2:35 PMSublingual Drug Delivery; Will It Always Give ‘Fast Onset'? A Product Enhancement Perspective
Jeremy A. Bartlett

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