Xuwei Jiang1, Hsien-Yeh Chen2, Mutsumi Yoshida3, and Joerg Lahann3. (1) Chemical Engineering, University of Michigan, 2300 Hayard St., 3309 G.G. Brown Building, Ann Arbor, MI 48105, (2) Chemical Engineering Department, University of Michigan, 2300 Hayward St, 3434 G.G Brown, Ann Arbor, MI 48109, (3) University of Michigan, Dept. of Chemical Engineering, 3074 H.H. Dow Bldg., Ann Arbor, MI 48109-2136
In this presentation, we demonstrate the surface-initiated atom transfer radical polymerization (SI-ATRP) from ATRP initiator coatings generated through CVD polymerization. ATRP initiator coatings were formed on a broad spectrum on substrates including gold, silicon wafer, glass, PMMA, polystyrene et. al. Subsequent SI-ATRP of poly(ethylene glycol) methyl ether methacrylate (PEGMA) resulted in the formation of polymer coatings of up to 300 nm thickness according to ellipsometric measurements. . XPS, AFM, and FT-IR confirmed the sequential formation of initiator coating and PEGMA coatings. Protein adsorption experiments conducted with Alexa Fluor 546-conjucated fibrinogen on micropatterned surfaces showed substantially reduced protein adsorption in regions where PEGMA coating is present. Owning to the versatility of CVD polymerization, this strategy is very versatile for modification of surfaces for a variety of applications.