Sunday, November 4, 2007
6bt

Computational and Experimental Studies of Protein-Self Assembly with Applications in Nanotechnology and Medicine

Troy Cellmer, Laboratory of Chemical Physics, National Institutes of Health, 9000 Rockville Pike, Building 5, Room 106, Bethesda, MD 20892

My research will be focused on protein self-assembly with applications in biomedicine and nanotechnology. On a fundamental level, it will involve uncovering mechanisms of self-assembly, as well as elucidating the relationship between peptide sequence and the structure of the resulting assemblies. This information will then be exploited to develop new therapies for assembly-related diseases, as well as fabricate novel nanomaterials.

As a graduate student my primary focus was computational studies of multi-protein systems. As a post-doc, I have utilized fluorescence spectroscopy to study ultra-fast protein folding. My research proposal relies on the convergence of both approaches, experimental and computational, to improve our basic understanding of assembly-related processes, and develop new technologies.